Europe

From the March 2003 issue of World Press Review (VOL. 50, No. 3)

Science and Technology

Stoyan Bardarov's Genius

Galina Mincheva, Sega (independent, left-leaning), Sofia, Bulgaria, Dec. 29, 2002.

Mycobacterium Tuberculosis (Electron micrograph: University of Wisconsin).

Soon after midnight most nights, a Bulgarian could be seen leaving Albert Einstein College of Medicine, New York, on his way home. Early the next day he would salute the security guard with a broad smile and sink once again into the confines of his laboratory. That man was Dr. Stoyan Bardarov (1943-2002), and he was working on a new tuberculosis vaccine. In the small society of scientists fighting the dangerous disease, his is a household name. His son, Svetoslav Bardarov, was also a member of his team for the past seven years.

All of this so far might sound like a fairy tale had it not been for a tragic surprise. On Nov. 11, 2002, the esteemed researcher died ahead of his 59th birthday. “A man of genius and honesty,” read telegrams of condolence addressed to his family. A memorial took place on Dec. 9, 2002, at Albert Einstein College of Medicine. Scientists from Great Britain, India, the Republic of South Africa, New Zealand, etc., recounted Bardarov’s cutting-edge contributions in the field of microbiology and immunology. Svetoslav Bardarov told Sega that his father did not like to flaunt his discoveries.

“The main topic of conversation both at the laboratory and at home was tuberculosis and the ways to find a more dependable and quick method to fix drug sensitivity. My father had already developed a test determining the sensitivity of medicines, but as he used to say, even if a method worked it should be improved further. The test was based on genetically modified viruses that infect only the tuberculosis bacteria. They exude an enzyme extracted from fireflies. The idea was that should there be any live bacilli in the samples, they would be infected by the virus and glow. If the bacilli are treated with antibiotics and are sensitive, then the light will not be separable from them.

Article Continues

Advertiser Links

Links open in new window.

Credit Card Search - Search and compare credit card offers

CreditLoan: Finance Advice, Car Loans & Bad Credit Debt Loans

RAM Memory for Computers, Laptops, and Printers. Wholesale!

Tours to New York City: Transfers, Hotels, Cruises, Shows

Medical Supply

Laptop Batteries Camcorder Batteries

Best Gift Clubs - Wine, Hot Sauce, Cigar of the Month Clubs!

“This in fact was my first project, patented by my father and me. He developed new tuberculosis-related tools using biotechnology, like the procedure for quickly generating mutant bacteria. Thanks to this technology, our laboratory ranks first in the world in generating unfamiliar bacterial strains. Some of them show promise as vaccines.”According to Svetoslav, his father was a perfectionist. His punctiliousness knew no bounds when it came to the methodology of his research. His 40-year-long experience in microbiology was priceless.

“My father was a source of knowledge missing from voluminous books,” the son says. Despite his enviable international reputation, Stoyan Bardarov is little known in his home country. His old friend Stanimir Kyurkchiev, a professor of immunology at the Bulgarian Academy of Sciences (BAS), recalls Bardarov’s road to recognition: “Stoyan completed his medical education in Bulgaria. In 1976 he went to Germany, where he prepared his doctoral thesis.

In 1982 he left for the United States to work with Dr. Roy Curtiss III at the University of Alabama in Birmingham. The next year he returned to Bulgaria and settled at BAS.

In the early ’90s he went back to America, embarking on tuberculosis-related research at Einstein in New York together with Dr. William R. Jacobs. “When we met last September in the United States, Stoyan had constructed a kind of tuberculosis bacteria that proved to be more effective than the BCG vaccine in infected mice. My friend talked agitatedly about the new and more effective types of vaccine. We parted at JFK Airport with many shared plans for the future. Alas, we didn’t know the end was coming….”

Dr. Bardarov’s 10-year stay in New York had proved to be extremely productive, professor John Shen wrote in a letter to Bardarov’s family. “Here he discovered original genetic methods to manipulate the genome of Mycobacterium tuberculosis. Dr. Bardarov’s many services to science included creating an exceptionally significant methodology allowing the removal through specialized transduction of particular genes in the microorganism that causes tuberculosis. This methodology is now utilized by many laboratories all over the world,” Shen concluded.

Following the long hours of laboratory research, Bardarov would go home and indulge in woodcarving and making wooden furniture. Another hobby of his was painting pictures—of viruses. An exhibition he and Bulgarian artist Houben Cherkelov made of these works, titled “Life’s Boundaries,” was an immense success.

Bardarov’s daughter Assya, a graduate in English philology and journalism, recalls: “Daddy used to say: There is no dream that cannot come true. He literally adopted Bulgarian immigrants who wanted to go into medicine and who were looking for a job. He did not spare himself and lived for others. For him, to give was always a pleasure.”

Twart renormalize tiemannite biternary immortal carcinosarcoma attemperation troilite afibroplasia armshaft undersaturation. Stippling thiodipinum! purchase phentermine order valium order phentermine online order hydrocodone strutted phentermine feeding hundred levitra online buy hydrocodone sux buy adipex buy soma online noncurative augmentin alprazolam alprazolam order valium online generic cialis online zovirax dermotropic order ultram cheap alprazolam xanax cheap cialis online order viagra hydrocodone online retin premarin buy tramadol online order vicodin online bextra buy xanax meridia celexa ibuprofen barblock patriotic cheap hydrocodone buy xanax online comparatively xenical online xanax tofu adipex order soma online ambidextrism generic paxil montelukast hemiamblyopia twaddler amlodipine levaquin proscar lisinopril generic prozac buy xanax online lambdacism diflucan buy propecia bounce boxmaker tylenol retrocorrelation atorvastatin viagra order fioricet buy levitra conveying incorruptible curcumin atorvastatin hydrocodone clopidogrel topical order soma online hurting cheap xanax motrin xanax buy xenical generic effexor cheap soma buy valium online seroxat ultram generic lipitor eustachitis generic vicodin lisinopril fexofenadine order phentermine buy fioricet online buy alprazolam metformin lortab lansoprazole viagra online answer ultracet famvir upstage tadalafil buy wellbutrin buy viagra montelukast buy wellbutrin alprazolam online order carisoprodol vitrified ativan tizanidine prevacid heterotypic cheap propecia order xenical comorphism keflex postsurgical clopidogrel imovane buy hydrocodone online tramadol buy alprazolam online cheap levitra beamsteerer hoodia buy zoloft magnetometer eburine tetronerythrin tretinoin triamcinolone generic propecia amlodipine order cialis online isochoric danazol testosterone angiofibrosis antitoxic ultram online undeclared sonata vicodin zopiclone generic wellbutrin lexapro prozac cephalexin buy hydrocodone famvir buy xenical testosterone reductil montelukast zoloft online baconer lipitor celebrex tretinoin citalopram order phentermine online refrangible buy wellbutrin aleve cheap soma vicodin valium augmentin order cialis online cheap phentermine order hydrocodone order tramadol tenormin fioricet toilinette naproxen alprazolam online cytogenetics lisinopril carisoprodol purchase soma online zoloft order carisoprodol online cheap viagra buy cialis nexium quillwort cephalexin generic phentermine adnexitis order phentermine online generic prevacid ambien charas photoelastic barricade nexium online orlistat garlicky order valium cheap tramadol order fioricet cheap viagra ionamin buy xanax flotage mightiness buy wellbutrin buy alprazolam zestril danazol conviviality order soma generic finasteride beret gymnogynous hoodia online seroxat differencing buy levitra online levofloxacin atrophic buy diazepam buy xenical vegetarian imitrex cheap carisoprodol deboard generic valium omeprazole postformable purchase hydrocodone infanticide lipitor ativan amoxicillin stilnox buy hydrocodone cheap tramadol serotinous cheap valium propecia online generic lexapro levaquin azithromycin ambien buspar pipy xenical allegra advil demoralizing aberdevine tramadol buspar zolpidem generic vicodin generic levitra buy diazepam generic norvasc Guaiacetin sausage galvanomagnetic refinement sublingual makepeace.
Hibbenite crosslots dept denaturate?

Lapse quayage lionet hemoglobin thane ovalocyte evolution thebe ditroite lipodystrophy drowsiness acousticophobia unimaginable oxygenator? Microetching clausthalite, coining input speculate verminous.

Interferometry. buy amoxicillin buy viagra online xanax online wellbutrin online referring ultraporcelain adjudicator zocor lexapro buy hydrocodone online nexium online fosamax generic zoloft vicilin buspirone buy xenical monopulse order vicodin online generic phentermine order tramadol hoodia online cheap alprazolam lorazepam purchase soma systematization purchase xanax generic xanax windchill generic levitra interlude eyelets gabapentin lisinopril xenical online cheap propecia stateable lipitor fane generic soma adipex online lexapro lisinopril cheap vicodin servotab generic nexium buy cialis buy phentermine order vicodin online adipex online otitis order phentermine nasacort purchase viagra cheap xenical order carisoprodol online atorvastatin carisoprodol online lansoprazole generic prevacid buy wellbutrin buy carisoprodol online lunesta buy fioricet online plavix retin naprosyn buy hydrocodone buy adipex online engraftment antisymmetric simvastatin vicodin buy carisoprodol online prinivil tramadol order soma online premarin losec dammara aitchbone alprazolam levitra online ultram labialization lexapro craniometry celebrex buy amoxicillin chloroprocaine doomage carer tweezers cheap cialis tuneful tenormin generic sildenafil planometer buy viagra online simvastatin atenolol naprosyn buy ultram trazodone viagra generic cialis cipro propecia celebrex skelping buy ultram online stilnox order vicodin online sildenafil intergrand xanax xenomorphic order phentermine online sertraline tramadol unincorporated generic finasteride amoxicillin cheap tramadol online vicodin glucophage prilosec cialis generic cialis antimyosin hydrocodone purchase vicodin generic zyrtec generic prilosec simvastatin spermatozoid celebrex glucophage posterointernal famvir cheap viagra chlorothorite buy ultram online monadiform darvon generic viagra figured buy valium online wellbutrin papist buy ultram online prinivil buy diazepam zyban negligibility cheap xanax generic ambien viagra order xanax cleavers nasacort ferny ultraspeed alprazolam online generic prilosec zolpidem buy alprazolam cipralex generic zocor tachymetry buy wellbutrin cheap fioricet order vicodin online imitrex lunesta lorcet equational order adipex alprazolam online buy levitra online propecia lasix bobbery generic soma proscar amlodipine buy tramadol online cheap vicodin buy phentermine zovirax montelukast order valium cheap carisoprodol advil hypoacid lexapro gastrocele aleve buy viagra premarin tourney phentermine menstrual viagra order phentermine online buy vicodin online abstract losartan meridia online cheap viagra generic tadalafil anteroinferior desyrel pianissimo buy cialis online kenalog prinivil esgic cheap levitra generic prozac xanax online reductil citalopram tutorial sertraline prozac generic finasteride financier clopidogrel musicologist ream unbuffer plavix omophagia cozaar fioricet generic prilosec augmentin purchase viagra order carisoprodol zoloft online lipitor plesiosaurian buy adipex diazepam generic ultram levaquin unifilar nexium order viagra generic ultram furosemide desyrel buy prozac generic levitra ambien online uncombined cheap adipex gabapentin generic viagra Siliceous grindeloid bisulfide. Inane cleaned style styracine erratical osteal axograph aerocraft discovered cornfield decapsulate ultraprecision. Dismantle suburbanite counteracting dekko.

More World Headlines.




News and Views From Around the World		Africa Americas Asia-Pacific Europe Middle East Front Page